Hydromorphone impurities and related standards

Hydromorphone is held here as a working collection of 15 reference materials across 5 CAS numbers. 3 of the entries are impurity-type materials of the parent, 2 are salt or counter-ion variants and 2 carry a deuterium label and 1 are nitrosamine analogues. 5 entries carry a verified structure drawing, a coverage of 33%; the rest are listed without a structure rather than with an unverified one. 4 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 11 remain tier C and are kept for search coverage. The lettered series exists because a pharmacopoeial monograph needed to name the impurities it controls, not because the letters follow any chemical order. Two suppliers can both claim coverage of a monograph and still hold different sets, so the comparison that matters is against the letter list in the monograph rather than against a catalogue heading. The mass balance check is the step most often skipped: the sum of the parent assay and the specified impurities should account for the sample, and a series that is incomplete makes that sum look better than it is.

Sources: DailyMed (US NLM) - HYDROMORPHONE HYDROCHLORIDE INJECTION, SOLUTION [FRESENIUS KABI USA, LLC].

8 reference standards related to Hydromorphone held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.

In this group: 2 impurity reference standards · 2 fine chemicals · 2 stable isotope labelled standards · 1 general reference standard. CAS numbers are listed for 8 of 8; 8 entries carry a structure drawing.

On this page

8 reference standards

All entries — structure, identifiers and pack sizes

Hydromorphone sulfate

CAS 25333-57-7C17H21NO7S

MW 383.1

IN STOCKRS-Z401GDH
10-hydroxy-hydromorphone

CAS not assignedC17H19NO4

MW 301.34

IN STOCKRS-H100004
8-Hydroxyhydromorphone

CAS 339525-94-9C17H19NO4

MW 301.34

IN STOCKRS-A002488
Hydromorphone 3-Sulfate

CAS 479081-35-1C17H19NO6S

MW 365.4

CUSTOM SYNTHESISRS-H100002
HYDROMORPHONE D3

CAS 136765-37-2C17H19NO3

MW 288.36

IN STOCKRS-I105236
HYDROMORPHONE D6

CAS 1024922-02-8C17H13D6NO3

MW 291.37

IN STOCKRS-I105231
Hydromorphone-3-glucuronide

CAS 40505-76-8C23H27NO9

MW 461.46

BACK ORDERRS-H100001
Norhydromorphone

CAS 14696-23-2C16H17NO3

MW 271.31

IN STOCKRS-I014224

8 reference standards

Frequently asked

How many Hydromorphone-related reference standards do you hold?

8 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 8 of them and 8 entries carry a structure drawing. The catalogue is extended as new lots are released.

Can you supply a Hydromorphone impurity that is not listed here?

Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.

What documentation is supplied with Hydromorphone impurities?

Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.

Do you publish prices or a lead time for Hydromorphone impurities?

No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.

Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.