Hydroxyzine impurities and related standards
Hydroxyzine is held here as a working collection of 45 reference materials across 19 CAS numbers. Within the range, numbered impurities go up to 21. 26 of the entries are impurity-type materials of the parent, 13 are salt or counter-ion variants and 5 carry a deuterium label. 15 entries carry a verified structure drawing, a coverage of 33%; the rest are listed without a structure rather than with an unverified one. 15 of them sit in tier A or B, meaning the data behind the page is complete enough to be indexed and quoted directly, while 30 remain tier C and are kept for search coverage. Relative response factors are what decide whether a percentage on a chromatogram means anything. Impurities that lack a chromophore, or whose ultraviolet maximum sits away from the detection wavelength used for the parent, under-respond by a factor that has to be established with a solution of the standard itself rather than assumed. For a laboratory setting specifications, the workable sequence is to fix the impurity list from the monograph and the degradation study first, and only then to source the standards, because the list determines which materials are worth holding.
Sources: DailyMed (US NLM) - HYDROXYZINE HYDROCHLORIDE SOLUTION [ADVAGEN PHARMA LIMITED].
22 reference standards related to Hydroxyzine held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 6 general reference standards · 4 fine chemicals · 4 impurity reference standards · 3 stable isotope labelled standards. CAS numbers are listed for 22 of 22; 22 entries carry a structure drawing.
On this page
22 reference standards
All entries — structure, identifiers and pack sizes
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Hydroxyzine
IN STOCKRS-U050165 -
Hydroxyzine dihydrochloride
CUSTOM SYNTHESISRS-U050102 -
Hydroxyzine Hydrochloride
CUSTOM SYNTHESISRS-H029002 -
1-[2-(2-Hydroxyethoxy)ethyl]piperazine.Dihydrochloride
IN STOCKRS-P030159 -
2-(2-chloroethoxy)ethanol
IN STOCKRS-C003089 -
Decloxizine Dihydrochloride
IN STOCKRS-Z396YQ9 -
Hydroxyzine EP Impurity B (HCl)
IN STOCKRS-A012083 -
Decloxizine in methanol
IN STOCKRS-M106108 -
Decloxizine-d8 Dihydrochloride
BACK ORDERRS-I097273 -
Hydroxyzine D4 Dihydrochloride
BACK ORDERRS-H004006 -
Hydroxyzine D8
CUSTOM SYNTHESISRS-H004039 -
Hydroxyzine in methanol
IN STOCKRS-Z412RXE -
Hydroxyzine N-Oxide
IN STOCKRS-U050110 -
Hydroxyzine Pamoate (1334006)
CUSTOM SYNTHESISRS-H004001 -
Hydroxyzine-d8DISCONTINUED
IN STOCKRS-Z412M4S -
Quetiapine HEEP Impurity
IN STOCKRS-Z397GBG -
Hydroxyzine Impurity 2 Dimaleate (Etodroxizine Dimaleate)
BACK ORDERRS-H004003 -
Hydroxyzine Impurity 7
CUSTOM SYNTHESISRS-H004040 -
Hydroxyzine Impurity 12 ((R)-Hydroxyzine)
IN STOCKRS-Z401E4X -
Hydroxyzine Impurity 13 ((S)-Hydroxyzine)
CUSTOM SYNTHESISRS-Z401E4W -
Hydroxyzine Impurity 20
IN STOCKRS-H004005 -
Hydroxyzine Impurity 21
IN STOCKRS-H004002
22 reference standards
Frequently asked
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Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.


![Chemical structure of 1-[2-(2-Hydroxyethoxy)ethyl]piperazine.Dihydrochloride](/structures/w4/JCYZKOJFYMJJTJ-UHFFFAOYSA-N.webp?v=8)















