Apixaban impurities and related standards
76 reference standards related to Apixaban held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
CAS numbers are listed for 76 of 76; 72 entries carry a structure drawing.
| Compound | CAS No. | Catalogue No. | Formula | MW |
|---|---|---|---|---|
| Apixaban Impurity D | 1074365-84-6 | RS-A032002 | C26H26N4O5 | 474.51 |
| Apixaban Impurity TQ | 1074549-89-5 | RS-A032004 | C25H23N5O4 | 457.48 |
| Apixaban Impurity 116 | 112176-22-4 | RS-A032005 | C6H11ClO2 | 150.6 |
| Apixaban Impurity 66 | 1192-28-5 | RS-A032006 | C5H9NO | 99.13 |
| Apixaban Impurity 80 | 123418-70-2 | RS-A032007 | C5H2Cl2O2S | 197.04 |
| Apixaban Impurity 50 | 1267610-26-3 | RS-A032008 | C15H19N3O2 | 273.33 |
| Apixaban Impurity 97 | 132577-23-2 | RS-A032009 | C12H14N2O4 | 250.25 |
| Apixaban Impurity 60 | 1351611-14-7 | RS-A032010 | C26H25N5O5 | 487.51 |
| Apixaban Impurity 20 | 1421823-20-2 | RS-A032011 | C27H29ClN4O5 | 525 |
| Apixaban Impurity 16 | 1423803-24-0 | RS-A032012 | C20H19N5O3 | 377.4 |
| Apixaban Impurity 19 | 1449510-64-8 | RS-A032013 | C25H26ClN5O4 | 495.96 |
| Apixaban Impurity 54 | 156-43-4 | RS-A032015 | C8H11NO | 137.18 |
| Apixaban Impurity 110 | 1562-94-3 | RS-A032016 | C14H14N2O3 | 258.27 |
| Apixaban Impurity 31 | 1619934-76-7 | RS-A032018 | C31H37N5O6 | 575.66 |
| Apixaban Impurity 61 | 1620386-62-0 | RS-A032019 | C26H29N5O7 | 523.54 |
| Apixaban Impurity 104 | 1642569-42-3 | RS-A032020 | C20H17N5O5 | 407.38 |
| Apixaban Impurity S2 | 1643330-62-4 | RS-A032021 | C20H26ClN3O3 | 391.89 |
| Apixaban Impurity BMS-728626-01 | 1686149-74-5 | RS-A032022 | C26H27N5O4 | 473.52 |
| Apixaban Impurity 17 | 1686149-78-9 | RS-A032023 | C21H27N3O3 | 369.46 |
| Apixaban Impurity 35 | 1686149-80-3 | RS-A032024 | C28H30N4O5 | 502.56 |
| Apixaban Impurity 106 | 1704504-93-7 | RS-A032025 | C20H18N4O4 | 378.38 |
| Apixaban Impurity I | 1777781-49-3 | RS-A032026 | C24H23N5O4 | 445.47 |
| Apixaban Impurity 76 | 1777782-33-8 | RS-A032027 | C26H26N4O5 | 474.51 |
| Apixaban Impurity 28 | 1801881-16-2 | RS-A032029 | C25H25N5O4 | 459.5 |
| Apixaban Impurity 36 | 1801881-17-3 | RS-A032030 | C24H23N5O3 | 429.47 |
| Apixaban Impurity 29 | 1801881-18-4 | RS-A032031 | C25H25N5O4 | 459.5 |
| Apixaban Impurity 33 | 1801881-22-0 | RS-A032032 | C27H28N4O5 | 488.54 |
| Apixaban Impurity 47 | 1904628-10-9 | RS-A032033 | C27H28N4O6 | 504.53 |
| Apixaban Impurity 83 | 19347-73-0 | RS-A032035 | C6H10Cl2O | 169.05 |
| Apixaban Impurity 79 | 1998079-12-1 | RS-A032036 | C40H34N10O7 | 766.76 |
| Apixaban Impurity 73 | 1998079-13-2 | RS-A032037 | C44H40N8O8 | 808.84 |
| Apixaban Impurity 74 | 1998079-14-3 | RS-A032038 | C44H40N8O9 | 824.84 |
| Apixaban Impurity 98 | 1998079-15-4 | RS-A032039 | C30H34N6O4 | 542.63 |
| Apixaban Impurity 99 | 1998079-16-5 | RS-A032040 | C30H34N6O5 | 558.63 |
| Apixaban Impurity S4 | 2029205-62-5 | RS-A032041 | C26H25ClN4O4 | 492.95 |
| Apixaban Impurity BMS-591329-01 | 2029205-64-7 | RS-A032042 | C24H22ClN5O3 | 463.92 |
| Apixaban Impurity BMS-778960-01 | 2098457-92-0 | RS-A032043 | C26H27N5O4 | 473.52 |
| Apixaban Impurity S3 | 2098457-93-1 | RS-A032044 | C21H27N3O3 | 369.46 |
| Apixaban Impurity BMS-724914-01 | 2187409-01-2 | RS-A032045 | C25H28N6O4 | 476.53 |
| Apixaban Impurity 111 | 2206360-55-4 | RS-A032046 | C27H28N4O4 | 472.54 |
| Apixaban Impurity 18 | 2206825-87-6 | RS-A032047 | C25H27N5O5 | 477.51 |
| Apixaban Impurity 90 | 2219376-48-2 | RS-A032048 | C11H9ClN2O3 | 252.65 |
| Apixaban Impurity 51 | 2228050-22-2 | RS-A032049 | C11H13ClN2O3 | 256.69 |
| Apixaban Impurity 65 | 2264018-89-3 | RS-A032051 | C25H26N4O6 | 478.5 |
| Apixaban Impurity 58 | 2413365-22-5 | RS-A032052 | C20H23N3O3 | 353.41 |
| Apixaban Impurity 63 | 2444918-46-9 | RS-A032053 | C15H19N3O2 | 273.33 |
| Apixaban Impurity 40 | 2512213-45-3 | RS-A032054 | C11H11ClN2O3 | 254.67 |
| Apixaban Impurity 69 | 2614-10-0 | RS-A032055 | C11H14N2O4 | 238.24 |
| Apixaban Impurity S1 | 27143-09-5 | RS-A032056 | C10H10Cl2N2O2 | 261.1 |
| Apixaban Impurity 119 | 2816305-40-3 | RS-A032057 | C15H17N3O2 | 271.31 |
| Apixaban Impurity 82 | 2818923-97-4 | RS-A032058 | C15H15N3O4 | 301.3 |
| Apixaban Impurity 118 | 405872-78-8 | RS-A032060 | C11H13ClN2O3 | 256.69 |
| Apixaban Impurity B | 473927-63-8 | RS-A032061 | C11H13ClN2O3 | 256.69 |
| Apixaban Impurity 93 | 503612-76-8 | RS-A032063 | C24H23N5O4 | 445.47 |
| Apixaban Impurity C | 503614-91-3 | RS-A032064 | C27H28N4O5 | 488.54 |
| Apixaban Impurity BMS-591455-01 | 503614-92-4 | RS-A032065 | C25H24N4O5 | 460.48 |
| Apixaban Impurity 49 | 503615-03-0 | RS-A032066 | C15H17N3O4 | 303.31 |
| Apixaban Impurity 21 | 503615-07-4 | RS-A032067 | C22H22N4O4 | 406.43 |
| Apixaban Impurity 62 | 536759-91-8 | RS-A032068 | C22H20N4O6 | 436.42 |
| Apixaban Impurity 103 | 536760-29-9 | RS-A032069 | C11H9ClN2O3 | 252.65 |
| Apixaban Impurity A | 545445-44-1 | RS-A032070 | C20H25N3O3 | 355.43 |
| Apixaban Impurity 115 | 63480-12-6 | RS-A032071 | C5H8Cl2O | 155.02 |
| Apixaban Impurity 52 | 70736-27-5 | RS-A032072 | C10H11ClN2O3 | 242.66 |
| Apixaban Impurity 72 | 813452-05-0 | RS-A032073 | C6H10Cl2O | 169.05 |
| Apixaban Impurity 39 | 881386-01-2 | RS-A032074 | C11H10Cl2N2O3 | 289.11 |
| Apixaban Impurity 105 | 881386-12-5 | RS-A032075 | C27H29BrN4O5 | 568.13 |
| Apixaban Impurity 71 | 99585-01-0 | RS-A032076 | C6H10Cl2O | 169.05 |
| Apixaban Impurity 15 | 1466571-07-2 | RS-A032014 | C21H20N4O4 | 392.42 |
| Apixaban Impurity 265 | 1589504-29-9 | RS-A032017 | C16H17ClN2O2 | 304.77 |
| Apixaban Impurity 54 | 1801881-15-1 | RS-A032028 | C11H11ClN2O | 222.67 |
| Apixaban Impurity 46 | 2228998-99-8 | RS-A032050 | C11H13ClN2O3 | 256.69 |
| Apixaban Impurity 130 | 28663-68-5 | RS-A032059 | C10H11ClN2O2 | 226.66 |
| Apixaban Impurity 37 | 1039914-85-6 | RS-A032001 | C11H13ClN2O3 | 256.69 |
| Apixaban Impurity H | 1074549-87-3 | RS-A032003 | C26H27N5O4 | 473.52 |
| Apixaban Impurity 108 | 1928718-22-2 | RS-A032034 | C26H27N5O4 | 473.52 |
| Apixaban Impurity 101 | 502144-05-0 | RS-A032062 | C10H14N2O2 | 194.23 |
Structures
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Apixaban Impurity D
COA per lot -
Apixaban Impurity TQ
COA per lot -
Apixaban Impurity 116
COA per lot -
Apixaban Impurity 66
COA per lot -
Apixaban Impurity 80
COA per lot -
Apixaban Impurity 50
COA per lot -
Apixaban Impurity 97
COA per lot -
Apixaban Impurity 60
COA per lot
Frequently asked
How many Apixaban-related reference standards do you hold?
76 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 76 of them and 72 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply an Apixaban impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Apixaban impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Apixaban impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.
Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to sales@rssechem.com.