Tofacitinib impurities and related standards
38 reference standards related to Tofacitinib held in the RSSE catalogue — pharmacopoeial impurities, non-compendial impurities, metabolites and labelled analogues where available.
In this group: 37 impurity reference standards · 1 fine chemical. CAS numbers are listed for 38 of 38; 28 entries carry a structure drawing.
| Compound | CAS No. | Catalogue No. | Formula | MW |
|---|---|---|---|---|
| Tofacitinib Impurity 10 | 1204176-45-3 | RS-T041007 | C8H16N2O2 | 172.22 |
| Tofacitinib Impurity 123 | 1243290-37-0 | RS-T041008 | C15H21N5O2 | 303.36 |
| Tofacitinib Impurity D | 1252883-90-1 | RS-T041009 | C20H25N5 | 335.45 |
| Tofacitinib Impurity 18 | 1260614-73-0 | RS-T041010 | C13H19N5·2HCl | 245.32 |
| Tofacitinib Impurity 13 | 1354469-76-3 | RS-T041011 | C7H16N2 | 128.22 |
| Tofacitinib Impurity 138 | 1404434-10-1 | RS-T041013 | C6H7N5 | 149.15 |
| Tofacitinib Impurity J | 1431697-80-1 | RS-T041014 | C14H22N22HCl | 218.34 |
| Tofacitinib Impurity 140 (Bromide) | 1615709-89-1 | RS-T041016 | C14H17N2.Br | 213.3 |
| Tofacitinib Impurity 140 | 1615709-90-4 | RS-T041017 | C14H17N2.Cl | 213.3 |
| Tofacitinib Impurity E | 1616760-97-4 | RS-T041018 | C13H18ClN5 | 279.77 |
| Tofacitinib Impurity G | 1616761-00-2 | RS-T041019 | C16H19ClN6O | 346.81 |
| Tofacitinib Impurity 112 | 1616761-01-3 | RS-T041020 | C17H23N5O3 | 345.4 |
| Tofacitinib Impurity 137 | 1629858-78-1 | RS-T041021 | C10H17N3O | 195.26 |
| Tofacitinib Impurity 153 | 1638499-36-1 | RS-T041022 | C15H20N2O | 244.33 |
| Tofacitinib Impurity 124 | 1640971-51-2 | RS-T041023 | C16H20N6O2 | 328.37 |
| Tofacitinib Impurity TBA | 1640971-60-3 | RS-T041024 | C14H20N6O | 288.35 |
| Tofacitinib Impurity N | 1640972-35-5 | RS-T041025 | C16H22N6O | 314.39 |
| Tofacitinib Impurity 122 | 1675248-18-6 | RS-T041026 | C18H25N5O3 | 359.42 |
| Tofacitinib Impurity Q | 1675248-19-7 | RS-T041027 | C16H22N6O2 | 330.38 |
| Tofacitinib Impurity 86 | 2183519-70-0 | RS-T041031 | C15H23N5 | 273.38 |
| Tofacitinib Impurity 45 | 2407039-29-4 | RS-T041032 | C16H20N6O2 | 328.38 |
| Tofacitinib Impurity Q | 3680-69-1 | RS-T041033 | C6H4ClN3 | 153.57 |
| Tofacitinib Impurity 85 | 372-09-8 | RS-T041034 | C3H3NO2 | 85.06 |
| Tofacitinib Impurity F | 384338-23-2 | RS-T041035 | C14H22N2 | 218.34 |
| Tofacitinib Impurity M | 477600-74-1 | RS-T041036 | C13H19N5 | 245.33 |
| Tofacitinib Impurity Z | 477600-76-3 | RS-T041037 | C15H21N5O | 287.37 |
| Tofacitinib Impurity R | 479633-63-1 | RS-T041038 | C13H10ClN3O2S | 307.76 |
| (3S,4R) Tofacitinib Citrate | 2174011-54-0 | RS-T041029 | C22H28N6O8 | 504.49 |
| (3S,4S)-Tofacitinib Citrate | 2174011-55-1 | RS-T041030 | C16H20N6O.C6H8O7 | 504.49 |
| Tofacitinib Impurity 5 | 1062580-52-2 | RS-T041001 | C14H22N2·2HCl | 218.34 |
| Tofacitinib Impurity 20 | 1092578-44-3 | RS-T041002 | C27H31N5O2S | 489.63 |
| Tofacitinib Impurity 22 | 1092578-45-4 | RS-T041003 | C20H25N5 | 335.45 |
| Tofacitinib Impurity A | 1092578-46-5 | RS-T041004 | C16H20N6O | 312.37 |
| Tofacitinib Impurity C | 1092578-47-6 | RS-T041005 | C16H20N6O | 312.37 |
| Tofacitinib Impurity B | 1092578-48-7 | RS-T041006 | C16H20N6O | 312.37 |
| Tofacitinib Impurity DT | 1354486-07-9 | RS-T041012 | C14H22N2·2HCl | 218.34 |
| Tofacitinib Impurity 88 | 145909-72-4 | RS-T041015 | C10H14N2O4 | 226.23 |
| (3R,4S)-Tofacitinib citirate | 2174011-53-9 | RS-T041028 | C16H20N6O : C6H8O7 | 312.4 |
Structures
-
Tofacitinib Impurity 10
COA per lot -
Tofacitinib Impurity 123
COA per lot -
Tofacitinib Impurity D
COA per lot -
Tofacitinib Impurity 18
COA per lot -
Tofacitinib Impurity 13
COA per lot -
Tofacitinib Impurity 138
COA per lot -
Tofacitinib Impurity J
COA per lot -
Tofacitinib Impurity 140 (Bromide)
COA per lot
Frequently asked
How many Tofacitinib-related reference standards do you hold?
38 standards are listed on this page as of the latest catalogue build. CAS numbers are published for 38 of them and 28 entries carry a structure drawing. The catalogue is extended as new lots are released.
Can you supply a Tofacitinib impurity that is not listed here?
Yes. Non-compendial impurities can be quoted from a structure — a CAS number is not required. Send the structure, a SMILES string or the parent drug substance with your enquiry and we will come back with availability.
What documentation is supplied with Tofacitinib impurities?
Every lot ships with its own certificate of analysis. The certificate records the catalogue number, the batch number, the tests performed, the specification applied and the result obtained for that lot. A safety data sheet is supplied with the shipment.
Do you publish prices or a lead time for Tofacitinib impurities?
No price list is published: quotations are prepared per enquiry, because availability and packing depend on the lot and the quantity you need. Send the catalogue number and the quantity and a technical contact will answer with availability and a quotation.
Cannot find the impurity you need? Non-compendial impurities can be quoted from a structure — a CAS number is not required. Write to [email protected].